Heavy Marijuana Use May Reduce Your Brain’s Dopamine Release

first_imgPsychology Today 15 April 2016Family First Comment: In a statement regarding the most recent study on heavy cannabis use and dopamine release, Jeffrey Lieberman MD, Chair of Psychiatry at CUMC and past president of the American PsychiatricAssociation, concluded, “these findings add to the growing body of research demonstrating the potentially adverse effects of cannabis, particularly in youth, at the same time that government policies and laws are increasing access and use.”   Yep!The March 2016 study, “Deficits in Striatal Dopamine Release in Cannabis Dependence (link is external),” was published in Molecular Psychiatry. For this study, an international team of researchers used positron emission tomography (PET) brain scans to track a radiolabelled molecule that binds to dopamine receptors in the brain. The scientists specifically measured dopamine release in the striatum and its subregions.The brain scans identified that severe marijuana dependence (now referred to as cannabis use disorder) is associated with a reduced release of dopamine within the striatum. The striatum is a brain region involved in working memory, impulsive behavior, and attention.The researchers believe that lower dopamine release within the striatum may be linked to the greater emotional withdrawal and inattention observed in marijuana-dependent study participants. Previous studies have found that addiction to other drugs, such as cocaine and heroin, have similar effects on dopamine release. However, this is the first study to provide evidence that heavy cannabis use may reduce dopamine release.In the brain, dopamine functions as a neurotransmitter which helps control the brain’s pleasure and reward centers. Dopaminergic pathways are neural pathways that transmit dopamine from one region of the brain to another. Dopamine drives reward-motivated behavior and helps us regulate movement and emotional responses.Dopamine not only enables someone to identify rewards, it gives him or her the oomph to seize the day and achieve goals. People with low levels of dopamine are statistically more prone to drug abuse, addiction, and amotivational syndrome (link is external).In the most recent study, the cannabis users had significantly lower dopamine release in the striatum, including subregions involved in associative and sensorimotor learning. The researchers also explored the relationship between dopamine release in key areas of the striatum and cognitive performance on learning and working memory tasks. Lower dopamine release was associated with subpar performance on both tasks.In a statement regarding the most recent study on heavy cannabis use and dopamine release, Jeffrey Lieberman (link is external), MD, Chair of Psychiatry at CUMC and past president of the American Psychiatric Association, concluded, “these findings add to the growing body of research demonstrating the potentially adverse effects of cannabis, particularly in youth, at the same time that government policies and laws are increasing access and use.”READ MORE: https://www.psychologytoday.com/blog/the-athletes-way/201604/heavy-marijuana-use-may-reduce-your-brains-dopamine-releaseKeep up with family issues in NZ. Receive our weekly emails direct to your Inbox.last_img read more

Palace won’t let up – Pulis

first_img “We have a responsibility to the Barclays Premier League and to the rest of the teams that we give the best we possibly can,” Pulis said. “We know our two games at home are going to be very difficult against two top teams and Fulham might still be fighting to get out of the bottom three – other teams around us expect us to put in a shift so it’s all to play for. “I hope there won’t be any let-up from the players. “I think the fact they are big games, especially the two home games which are on television as well, gives the lads the opportunity to show everyone how well they’ve been playing and they have been playing well.” Marouane Chamakh and Kagisho Dikgacoi are both trying to shake off knocks as Crystal Palace host Manchester City in the Barclays Premier League on Sunday. David Silva and winger Jesus Navas will both miss Manchester City’s trip with ankle injuries, but Yaya Toure should be available again to bolster the midfield. Toure suffered a muscle injury in the 3-2 defeat to Liverpool earlier this month but is now ready to return for the Blues. Defender Matija Nastasic, out of action since February because of a knee injury, remains out. Manchester City boss Manuel Pellegrini has said there has never been any concern that the club would be excluded from the Champions League for breaching UEFA’s financial fair play (FFP) rules. UEFA president Michel Platini has said he does not think any of the 20 clubs who are being investigated for breaches will be banned form European competition next season. City have been working closely with UEFA to try to ensure they comply with spending rules, which limit losses to 45million euro (£37million) over the last two years. Pellegrini said: “I felt here inside the club nobody feared we could be suspended for next year.” City insiders say they are confident that they will not face severe action from the European governing body. Any sanctions are likely to be made public at the end of next week. Meanwhile, Pellegrini believes Sergio Aguero’s return from injury could prove crucial as City try to push Liverpool all the way in the title race. City travel to Crystal Palace on Sunday knowing that they must win if they are to have any chance of beating Liverpool to the league title. Pellegrini said: “It is very good to have him back because I always say Sergio is a good player, he is important, he makes a difference. Always he is very important for the team.” The Eagles, who are 11th in the table, achieved their objective of survival in the top flight when they beat West Ham 1-0 last Saturday. Pulis’ side could still have a major influence on matters at both ends of the league, however, with Sunday’s match against Manchester City coming before another home game against league leaders Liverpool and a visit to relegation-battling Fulham on the final day. Crystal Palace manager Tony Pulis believes the title race is still wide open and insists his players have a responsibility to the Barclays Premier League to give their all until the end of the season. Press Associationlast_img read more


first_imgThe following incidents were reported in the USC Dept. of Public Safety incident report summary between Monday, Sept. 23, and Tuesday, Sept. 24. Crimes against personsat 8:57 a.m. on Sept. 23, two Bovard Administration Building staff members reported that a non-USC affiliated man had been rude to them over the phone and in person while complaining about issues he has had with the school.At 9:36 a.m. on Sept. 23, a staff member reported that a student she asked not to contact her continues to do so.Miscellaneous incidentsat 9:01 a.m. on Sept. 23, a Bovard Administration Building staff member reported to DPS that a suspicious man carrying a duffel bag entered the building and asked to meet with the president of USC. After being advised that he needed to make an appointment for a meeting, the suspect left. DPS could not locate him.at 9:07 a.m. on Sept. 23, a student cut his chin when he fell off of his scooter. DPS officers transported him to the Student Health Center for treatment. at 11:33 a.m. on Sept. 23, a male who is not a USC student jumped off his bicycle at the Exposition Boulevard parking structure in order to avoid a collision with a vehicle. The bicycle rolled into the vehicle, causing damage.at 12:00 P.M. on Sept. 23, a non-USC female was treated by EMTs at the Coliseum after a bottle was dropped on her head from the section above her. The woman believes that the incident is evidence of a larger safety issue and requested a report.at 1:53 p.m. on Sept. 23, DPS officers transported a student who had cut her finger while slicing an avocado at University Gateway Apartments to the Student Health Center for treatment.at 6:10 p.m. on Sept. 23, a man reported that someone had set a coffee cup with lighter fluid in it on fire on a kitchen table. DPS was unable to find a suspect.at 8:48 p.m. on Sept. 23, DPS officers transported a student who had injured her finger playing basketball at the Lyon University Center to Good Samaritan Hospital for treatment.at 12:06. a.m. on Sept. 24, two students were caught smoking marijuana in a Pardee Tower dorm room and cited to Judicial Affairs for the offense.last_img read more