Traore and Pino play in QPR Under-21 game

first_imgArmand Traore and Yelko Pino are playing for QPR’s development side in a match against Charlton this afternoon.Traore has not played a first-team match this season – and has made just one appearance for Rangers in more than a year.West London Sport recently revealed that Celta Vigo midfielder Pino, 19, was on trial with the R’s and would play in two Under-21 matches. He subsequently featured in a game against Millwall last week.Celta Vigo announced last month that the Spain Under-19 international had joined QPR on a six-month deal.The La Liga club previously announced he had moved to Swindon Town, where he also trained but did not sign.See also:Spanish midfielder training with QPR ahead of possible moveQPR’s second-half display angers HasselbainkYun praised by Charlton boss RigaRangers assess Hall foot injuryMK Dons v QPR player ratingsTraore and Pino play in QPR Under-21 gameFollow West London Sport on TwitterFind us on Facebooklast_img read more

Photo library: Buildings and structures 9

first_img{loadposition tc}Click on a thumbnail for a low-resolution image, or right-click on the link below it to download a high-resolution copy of the image.» Download Buildings & Structures contact sheet (1.1MB) » Download full image library contact sheet (10.5MB) Western Cape province:Waterford Wine Estate near Stellenbosch.Photo: Stellenbosch Wine Routes » Download high-res image Western Cape province:Wine cellar at Annex Kloof Wines in the Swartland region.Photo: Swartland Wine Routes » Download high-res image Western Cape province:Org de Rac Domain wine farm in the Swartland region.Photo: Swartland Wine Routes » Download high-res image Kimberley, Northern Cape province: The eye-catching architecture of the Northern Cape Provincial Legislature in Galeshewe. Kimberley is the capital of the province. Photo: Graeme Williams, MediaClubSouthAfrica.com » Download high-res image Kimberley, Northern Cape province: The eye-catching architecture of the NorthernCape Provincial Legislature in Galeshewe. Kimberley is the capital of the province. Photo: Graeme Williams, MediaClubSouthAfrica.com » Download high-res image Kimberley, Northern Cape province: The eye-catching architecture of the NorthernCape Provincial Legislature in Galeshewe. Kimberley is the capital of the province. Photo: Graeme Williams, MediaClubSouthAfrica.com » Download high-res image Kimberley, Northern Cape province: The tourist area surrounding the famous Big Hole, a former diamond mine and the largest hand- dug open-cast mine in the world. Photo: Graeme Williams, MediaClubSouthAfrica.com » Download high-res image Kimberley, Northern Cape province: An exhibit at the tourist area at the famous Big Hole, a former diamond mine and the largest hand- dug open-cast mine in the world. Photo: Graeme Williams, MediaClubSouthAfrica.com » Download high-res image Kimberley, Northern Cape province: An exhibit at the tourist area at the famous Big Hole, a former diamond mine and the largest hand- dug open-cast mine in the world. Photo: Graeme Williams, MediaClubSouthAfrica.com » Download high-res image BUILDINGS AND STRUCTURES 9: {loadposition bd}Having trouble downloading high-resolution images? Queries about the image library? Email Janine Erasmus at janinee@mediaclubsouthafrica.com.last_img read more

New protein for gene editing may improve disease treatment, crops, sustainable manufacturing

first_imgShare Facebook Twitter Google + LinkedIn Pinterest Gene editing has been a much sought after and controversial technology. Last month, part of the World Health Organization called for an international registry to track all research into editing the human genome.Purdue University researchers have developed a new technology that could change how gene editing is approached. NgAgo is programmed with guide DNA (red) to cut DNA (purple) at specific regions, enabling precise genetic modifications. (Image provided)Purdue University researchers, including one who was inspired by the cancer death of a close friend, have developed a new technology that could change how gene editing is approached in the future. The research team presents the work on April 4 at the National Meeting of the American Chemical Society in Orlando.One of the most widely used methods for gene editing is CRISPR-Cas9 technology. The method requires a certain sequence or motif for function that restricts modifications.“CRISPR can be programmed to cut DNA at specific regions to make precise edits in an organism that can increase sustainable manufacturing, treat disease and even create better crops,” said Kevin Solomon, an assistant professor of agricultural and biological engineering, who leads the Purdue research team. “However, it requires a certain sequence for function that restricts modifications to certain regions.”Many diseases in humans, including several types of cancer, are caused by mutations at specific sites in the genome. The Purdue team created a method that uses the protein Argonaute from Natronobacterium gregoryi (NgAgo) and supplied DNA as a guide to enable modification anywhere on the genome, providing new options to potentially improve manufacturing, disease treatment, drug discovery and crop production.“While there is still work to do, we have shown that these molecular scissors can edit regions of DNA previously inaccessible by current technologies,” said 2nd Lt. Michael Mechikoff, a master’s student working on the project.“One of my best friends died from a cancer caused by a genetic variant several years ago,” said Kok Zhi Lee, a doctoral student who works on the research team in Solomon’s lab. “I always dreamed of a different scenario for my friend — living in an era where genetic engineering is a regular and safe option to correct genetic disorders. With the potential of our technology, I anticipate a future where genetic disease is history for human beings.”The team has worked with the Purdue Research Foundation Office of Technology Commercialization to file a utility patent on the technology. They are looking for partners and others interested in developing and licensing it.last_img read more

Google Brings the Power of the Pie Chart

first_imgIf you’ve ever sat around mulling over different parts of an interactive map after an election or studied the New York Time’s “How Different Groups Spend Their Day” graph, then you know the value of a good chart. They can suck users in and really engage them. They can take a complex concept and make it simple.Google’s latest release, the Google Chart Tools, will make it easier for sites to show their users data in a meaningful, visual and interactive manner.These tools are broken down into two parts: image charts and interactive charts. The image charts work off a simple URL structure, defining all of the necessary characteristics through URL parameters. The interactive charts, while still relatively simple compared to custom creation, use a slightly more complicated Javascript library. Interactive charts will allow for showing extra data on mouseovers and simple animation. There are 30 different chart styles available, from interactive maps to pie charts, line charts to Venn diagrams.According to the Google Code Blog, “Interactive charts trigger events, providing tool-tips and animations. In addition to a rich gallery of charts, this tool can also read live data from a variety of data sources such as Oracle PL/SQL or Google spreadsheets.”We’re hoping these take off and we see more interesting visual data sets to play with around the web in the very near future. Why Tech Companies Need Simpler Terms of Servic… 8 Best WordPress Hosting Solutions on the Market Related Posts Top Reasons to Go With Managed WordPress Hostingcenter_img A Web Developer’s New Best Friend is the AI Wai… mike melanson Tags:#design#Google#news#web#Web Development last_img read more

9 days agoSpain coach Moreno dedicates Euros qualification to Luis Enrique

first_imgAbout the authorCarlos VolcanoShare the loveHave your say Spain coach Moreno dedicates Euros qualification to Luis Enriqueby Carlos Volcano9 days agoSend to a friendShare the loveSpain coach Robert Moreno has dedicated Euros qualification to Luis Enrique.La Roja have made the 2020 Euros after their 1-1 draw with Sweden.And Moreno says qualification is tribute to former Barcelona coach Enrique, who stepped down earlier this year to be with his daughter before her passing.Moreno said, “We have played a good game, and even if we had lost, I would have been happy. Because we have played more with our style. We are qualified and now we have to try to be the top of the group.”Spain is a high-level national team and qualification is a must, but achieving it has its value I want to take the opportunity to dedicate this to Rubiales and Molina because they trusted me, and also Luis Enrique. “It releases tension and doubt, and gives us time to work more comfortably, but without losing tension because the goal is to be one of the six best to go to the draw as seeded teams. It will not be easy, but we will try.” last_img read more

Conservatives halt allnight voting marathon vow to resume fight next week

first_imgOTTAWA – The Conservatives vowed Friday to employ new tactics next week to force testimony from Justin Trudeau’s national security adviser over the prime minister’s recent trip to India.The Tories made the pledge after ending a marathon overnight voting session that began Thursday and kept members of Parliament answering roll calls in the House of Commons for nearly 21 hours.Conservative House leader Candice Bergen called a halt to the procedural stunt after MPs had voted on hundreds of motions deemed confidence measures. After she did, the calendar on the clerk’s desk finally flipped over to Friday and the sitting wrapped up.Bergen thanked parliamentary staff, from the Speaker to security guards to cafeteria workers, for hanging on through the prolonged sitting.Soon afterwards, the bleary MPs — some clad in sweats and clutching pillows and blankets — emerged from the chamber pumping their fists in the air in a victory gesture.At issue was the Liberal government’s refusal to support a Conservative demand that national security adviser Daniel Jean be called to testify before a Commons committee about a briefing he gave journalists during the prime minister’s ill-starred visit to India.Jean suggested to reporters covering Trudeau’s trip last month that rogue factions in the Indian government had sabotaged the visit. Since then, Opposition MPs demanded that Jean explain his reasoning about how one-time Canadian Sikh separatist and convicted attempted murderer Jaspal Atwal was invited to a Trudeau event in India.Atwal’s appearance, and Jean’s statements about the Indian government, have harmed Canada-India relations, said Conservative foreign affairs critic Erin O’Toole.“We’ve already seen the Indian government express outrage, raise tariffs,” said O’Toole.“We’ve angered a major Commonwealth partner … and the prime minister clings to this conspiracy theory that directly contradicts his own MP, Randeep Sarai.”While Trudeau has defended Jean as a professional, non-partisan, veteran public servant who only says what he knows to be true, Sarai took responsibility for getting Atwal on the guest lists for Trudeau events in India after Atwal said he requested an invitation.Only one of those two scenarios can be true, said O’Toole: either Atwal was invited by a Liberal MP or he was an Indian government plant and Jean should be allowed to testify so he can clear the air over the controversy.But Liberal House Leader Bardish Chagger said it was entirely up to MPs on the national security committee — the majority of whom are Liberals — to decide whether Jean should be called to testify.“The committee should be able to choose if they would like him to come and testify or not,” said Chagger. “And that’s a choice for committee members to make.”NDP members, however, noted that the committee had not voted on a motion to compel Jean to testify. Instead, committee members adjourned debate before a vote could be called.Either way, it’s up to Trudeau to “come clean with Canadians about his trip to India,” Bergen said in a statement.“Canadians deserve to know the truth about what happened during the Atwal Affair,” she said. “Justin Trudeau is trying to hide the one person who can set the record straight. That’s not right.”O’Toole insisted the fight will carry on next week, although he wouldn’t say what new tactics his party might use.“We’re going to bring this back in a new way,” said O’Toole.last_img read more

Hoda Kotb Tia Mowry Team Up To Eat Dessert First For Childrens

first_imgFans can come up with several reasons for why it’s good to eat dessert first. But the Dairy Queen system has come up with the best reason yet.On Thursday, July 27, for that day only, the Dairy Queen system is encouraging fans to Eat Dessert First during the 12th Annual Miracle Treat Day, when $1 or more from every Blizzard Treat sold at participating DQ Grill & Chill and Dairy Queen locations throughout the U.S. will be donated to local Children’s Miracle Network Hospitals (CMNH).Annually at CMNH one in 10 children is treated and 32 million treatments are provided. Funds raised during Miracle Treat Day fund critical treatments and healthcare services, pediatric medical equipment and charitable care to help save and improve the lives of those children. While CMNH raises funds and awareness for more than 170 children’s hospitals across the U.S. and Canada, all funds raised during Miracle Treat Day stay in local communities.“When you visit a Children’s Miracle Network Hospital, you are inspired by how brave the children and their families are,” said Barry Westrum, executive vice president of marketing for American Dairy Queen Corporation (ADQ). “Then you see how passionate the doctors and nurses are and you realize what a significant impact the dollars we raise can have on so many lives. We have two great moms this year, Hoda Kotb and Tia Mowry, who are joining us in supporting Miracle Treat Day.”New mom and co-anchor of the fourth hour of Today, Hoda Kotb is the honorary chair of Miracle Treat Day. Kotb has ties to CMNH. She lifted the spirits of children with cancer and raised money for pediatric cancer as part of Today’s Shine a Light series a few years ago that included the shooting of a music video with pediatric patients at The Children’s Hospital of Philadelphia, part of the CMNH network.Also this year, Tia Mowry, actress, cookbook author and mom, will deliver Blizzard Treats and visit with patients and their families at Children’s Hospital Los Angeles in advance of the DQ Miracle Treat Day.“July is a special month for the Dairy Queen system. It’s National Ice Cream Month and we are celebrating by giving back to our local communities in a big way with Miracle Treat Day,” said Westrum. “We thank Hoda and Tia for their support of Children’s Miracle Network Hospitals and can’t wait to raise money on Miracle Treat Day.”Last year, DQ operators across the U.S. and Canada raised more than $4 million on Miracle Treat Day for their local CMN Hospitals. Since 1984, the Dairy Queen system has raised more than $125 million for the charity through fundraising efforts including Miracle Treat Day, the Miracle Balloon campaign and other local initiatives.The featured Miracle Treat Day Blizzard Treat of the Day is Oreo, the most popular Blizzard Treat to date. All other Blizzard flavors are also available that day.For more information about Miracle Treat Day, visit MiracleTreatDay.com and connect on Twitter using #MiracleTreatDay.For more information about the Dairy Queen system, visit DairyQueen.com.last_img read more

Opensource solution for multiparametric optical mapping of the hearts electrical activity

first_img Source:https://mipt.ru/english/news/open_source_solution_researchers_3d_print_system_for_optical_cardiography Reviewed by James Ives, M.Psych. (Editor)Mar 22 2019An international research team from the George Washington University, U.S., and the Moscow Institute of Physics and Technology, Russia, has developed an open-source solution for multiparametric optical mapping of the heart’s electrical activity. The technique involves monitoring multiple parameters at once — for example, both electrical excitation and the changes in the intracellular calcium concentration. This technique is a useful tool for enhancing our understanding of the mechanisms behind cardiac arrhythmias. The 3D models of the mapping system components and the source code for data analysis are openly available, enabling other research groups to benefit from the new solution. The study was published in Scientific Reports.Cardiac excitation-contraction involves numerous interacting phenomena, primarily electrical excitation and the variation in calcium concentration. Normally, excitation is initiated by a group of cells in the right atrium, called the sinoatrial node, and spreads through the cardiac conduction system to the atria and ventricles (figure 1). Abnormalities in propagation, known as arrhythmias, are a leading cause of mortality in Russia and other developed countries.Optical mapping is currently the leading technique for investigating the mechanisms behind arrhythmias. This technique is based on perfusing ex vivo whole heart or a slice of cardiac tissue with fluorescent dyes. A number of intracellular parameter changes could be tracked this way using high-speed cameras. The high cost of the equipment and the technical challenges of monitoring multiple parameters of the sample at once and processing the associated signals prevent more widespread use of optical mapping in the biological community.To address this, the authors of the paper developed an open-source and expansible system that simultaneously tracks cardiac electrical excitation and intracellular calcium dynamics. Every system component, excluding cameras, lenses, and pumps, was 3D-printed. Since the designs of all components are now openly available, any laboratory can recreate a similar tool. The authors calculated that this could save other researchers up to $20,000, compared with commercially available products. Along with the designs, the team open-sourced the code of their Matlab-based RHYTHM software for signal processing.Related StoriesTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTRepurposing a heart drug could increase survival rate of children with ependymomaResearch opens possibility of developing single-dose gene therapy for inherited arrhythmias”We made it a priority that physiologists would have access to the software, because they may lack the programming skills needed to code in C++, for example,” comments study co-author Roman Syunyaev, a leading researcher at MIPT’s Human Physiology Lab. “The current version of the software has a number of modules for analyzing the action potential and calcium transients [figure 2]. But the architecture allows one to add a new module to enable simultaneous measurement of metabolic changes (NADH concentration), for example.””Although the excitation propagation in the heart muscle is associated with an interaction between multiple complex phenomena, it is usually the case that researchers can only measure one parameter. Studies using multiparametric mapping are still uncommon,” adds Syunyaev.”Our laboratory maintains an open data policy,” says professor Igor Efimov of the George Washington University, who also heads the Human Physiology Lab at MIPT. Not many research teams nowadays can afford the expensive equipment for optical mapping. Now they can use our designs to recreate an affordable system just like the one we used. And they can process the data with RHYTHM. A further advantage of our tool is that it offers the freedom to design new experiments on diverse samples.”last_img read more

A smart safe rechargeable zinc ion battery based on solgel transition electrolytes

first_img More information: Funian Mo et al, A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes, Science Bulletin (2018). DOI: 10.1016/j.scib.2018.06.019 Polymer professor develops safer component for lithium batteries Reversible sol-gel transition hydrogels have received abundant research interest owing to their smart response to ambient temperature. They are normally in flowing liquid state at or below room temperature and can transform into stationary gels when heated above a critical temperature. Moreover, this transition can be reversed after cooling down, displaying interesting temperature-dependent properties. Sol-gel transition polymers may potentially be good candidates for designing advanced batteries with intelligent thermal responsibility.Recently, a research team led by Prof. Chunyi Zhi from City University of Hong Kong has successfully synthesized a temperature-sensitive sol-gel transition electrolyte comprising proton-incorporated poly(N-isopropylacrylamide-co-acrylic acid) (PNA). They incorporated it into a rechargeable Zn/α-MnO2 battery system. After heating above the low critical temperature, a gelation process occurs in the PNA sol-gel electrolyte and significantly inhibits the migration of zinc ions, leading to a decreased specific capacity and an increased internal resistance of the battery, thus shutting down the battery.After cooling down, the transition is reversed to liquid state and an original electrochemical performance can be restored. More importantly, unlike traditional strategies, the sol-gel electrolyte endows the thermoresponsive battery with dynamic charge/discharge rate performance at different temperature, enabling “smart” thermal control for the battery. This work represents a feasible concept for self-protection batteries via reversible sol-gel transition. Explore further Dynamic electrochemical performance the thermoresponsive Zn/α-MnO2 batteries at different temperature. Credit: ©Science China Press Provided by Science China Presscenter_img This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Schematic illustration of the thermoresponsive Zn/α-MnO2 batteries with reversible sol-gel transition electrolye. Credit: ©Science China Press Citation: A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes (2018, July 20) retrieved 18 July 2019 from https://phys.org/news/2018-07-smart-safe-rechargeable-zinc-ion.html The thermal runaway issue has been a longstanding obstacle impeding the development of high-energy-density, high-power delivery batteries. These batteries would generate a lot of heat in ultrafast charge/discharge process or hazardous conditions, such as overcharging and short-circuits. To dissipate the heat accumulated in the batteries, physical safety designs such as fused disconnect switches, extinguishing agents, and shutdown current collectors have been employed. However, these approaches only provide one-time protection. There is no provision for these strategies to spontaneously restore the original working condition of batteries once the temperature is cooled down. Therefore, intelligent and active internal safety strategies are required for fabricating smart batteries with dynamic electrochemical performance and self-adaptive response to temperature.last_img read more

A Pair of Shipwrecked WWIIEra Submarines Just Vanished from the Sea Near

first_imgMore than 100 World War II-era shipwrecks decorate the seafloor around Indonesia, Malaysia and Singapore — and now, there are two fewer. According to Dutch media reports, a pair of submarines that sank off the coast of Malaysia in 1941 mysteriously vanished late last week, leaving behind only some broken scraps and ghostly outlines in the sand. The wrecked subs — Dutch vessels named HNLMS O 16 and HNLMS K XVII — also contained the remains of 79 crewmen, which are now missing. [17 Mysterious Shipwrecks You Can See on Google Earth] How does a shipwreck simply disappear? According to Dutch government officials, the subs were likely stolen by scrap-metal scavengers, who have made a habit of pilfering old wrecks from the region. As many as 40 World War II-era ships have been partially or completely dismantled by scavengers, a 2017 report by the Guardian found, resulting in the desecration of the remains of some 4,500 crewmen who went down with their ships.Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65894-dutch-wwii-era-submarines-vanished.html?jwsource=cl已复制直播00:0000:3500:35  Salvaging a shipwreck usually requires blowing the vessel apart with explosives, then spending days or weeks hauling any valuable metals up onto the surface with a crane. For their trouble, scavengers can come away with millions of dollars’ worth of steel per ransacked ship, plus other spoils, such as copper cables and phosphor bronze propellers, according to the Guardian article. Wartime shipwrecks are protected under international treaties as the unmarked graves of departed soldiers — however, that has not stopped salvagers from destroying the wrecks of the American, British, Dutch, English, Australian and Japanese vessels resting in South East Asian waters. In March 2018, Malaysian officials signed an agreement with the Dutch foreign minister to better protect Dutch war wrecks in Malaysia’s waters. (Parts of Malaysia were once under Dutch colonial rule.) The agreement followed a string of particularly serious shipwreck desecrations; in 2016, the wrecks of three Dutch warships vanished from the bottom of the Java Sea off the coast of Indonesia, along with the remains of 2,200 people, the Guardian reported. Shipwrecks Gallery: Secrets of the Deep Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoNucificTop Dr. Reveals The 1 Nutrient Your Gut Must HaveNucificUndoLivestlyThe List Of Dog Breeds To Avoid At All CostsLivestlyUndoEditorChoice.comSee What The World’s Largest Dog Looks LikeEditorChoice.comUndo In Photos: Diving for a Famed Roman Shipwreck Disasters at Sea: 6 Deadliest Shipwreckslast_img read more